ea0047oc37 | Innovative Theranostics | Theranostics2016
Donnelly Paul
, Paterson Brett M
Radioactive isotopes of copper are of interest in the development of imaging agents for positron emission tomography (PET) and companion therapeutics. The synthesis of a ligand, 5-(8-methyl-3,6,10,13,16,19-hexaaza-bicyclo[6.6.6]icosan-1-ylamino)-5-oxopentanoic acid (MeCOSar), designed to form stable complexes with radioactive copper isotopes that can be tethered to tumour targeting peptides and antibodies will be presented.The MeCOSar ligand has been con...